Cerebral Perfusion in Neonates
Research type
Research Study
Full title
Cerebral Perfusion in Neonates following Intervention for Acute Respiratory Failure.
IRAS ID
240082
Contact name
Helen Jones
Contact email
Sponsor organisation
Liverpool John Moores University
Duration of Study in the UK
2 years, 6 months, 8 days
Research summary
The most common reason for admitting babies and infants to an intensive care unit is due to respiratory distress (breathing difficulties). At present there are a number of different treatments for respiratory distress. These include drug treatments; non-invasive ventilation, where oxygen is given at high pressure to push it through the baby's lungs: ventilation where the baby is put on a breathing machine; or Extracorporeal Membrane Oxygenation (ECMO). This works by taking the blood from the body via a tube (usually) in the baby's neck, redirecting through a machine that oxygenates the blood, then returning it to the baby through another tube. Currently we know little about how different treatments have a different impact on brain perfusion (how much oxygen the brain gets). Using specialist, non-invasive ultrasound and doppler techniques, we are proposing to monitor the effect of these treatments on the brain.
REC name
North West - Liverpool Central Research Ethics Committee
REC reference
18/NW/0461
Date of REC Opinion
5 Sep 2018
REC opinion
Further Information Favourable Opinion