Cerament study 2
Research type
Research Study
Full title
Post-market study of Cerament V/G in foot osteomyelitis
IRAS ID
339714
Contact name
Ankur Thapar
Contact email
Sponsor organisation
Mid and South Essex Foundation Trust
Clinicaltrials.gov Identifier
Clinicaltrials.gov Identifier
IRAS number , 339714
Duration of Study in the UK
2 years, 2 months, 30 days
Research summary
Foot bone infection is common, difficult to treat and may lead to amputation.
In our recent study we compared an older and newer treatment for foot bone infection.
• Conventional treatment was 6 weeks of high dose intravenous antibiotics given through a home intravenous line.
• Treatment 2 was antibiotic paste injected directly into the affected bone with 1 week of oral antibiotics.
We found over a 6 month period that treatment 2 was at least as effective, but had less treatment limiting side-effects such as diarrhoea, had better adherence to treatment and was more convenient for patients and hospitals.
We now wish to follow 25 patients treated with antibiotic paste for 1 year to look at how effective it is at preventing recurrent bone infection, both clinically and on x-ray.REC name
West Midlands - Black Country Research Ethics Committee
REC reference
24/WM/0161
Date of REC Opinion
13 Aug 2024
REC opinion
Further Information Favourable Opinion