CENTAUR

  • Research type

    Research Study

  • Full title

    Characterising the Centralised Pain Phenotype in Chronic Rheumatic Disease - A Stride Towards Personalised Analgesia

  • IRAS ID

    257990

  • Contact name

    Neil Basu

  • Contact email

    neil.basu@glasgow.ac.uk

  • Sponsor organisation

    NHS Greater Glasgow and Clyde

  • Duration of Study in the UK

    2 years, 9 months, 0 days

  • Research summary

    Many patients with arthritis continue to experience significant pain even after receiving optimal arthritis specific therapies. We believe this discrepancy relates to the co-existence of more than one cause of pain. In particular we think that pain originating in the central nervous system (CNS) is likely to be common and responsive to very different types of therapy. First, we seek to derive biological and clinical evidence that this distinct type of pain is important in psoriatic arthritis (PsA) by undertaking a) routine clinical assessments b) questionnaires c) MRI brain scans d) tests of pain sensitivity . Thereafter we will use this information to develop tools which will measure this pain type across chronic musculosketal diseases.

  • REC name

    West of Scotland REC 3

  • REC reference

    19/WS/0033

  • Date of REC Opinion

    14 Mar 2019

  • REC opinion

    Further Information Favourable Opinion