CCLG Tissue Bank (2018 BS 03) (v1.0)

• Research type

  Research Tissue Bank

• IRAS ID

  243323

• Research summary

  Children's Cancer and Leukaemia Group (CCLG) Tissue Bank
  (2018 BS 03)

• REC name

  East Midlands - Derby Research Ethics Committee

• REC reference

  18/EM/0134

• Date of REC Opinion

  25 Jun 2018

• REC opinion

  Further Information Favourable Opinion

• Data collection arrangements

  The CCLG Tissue Bank aims to store tissue samples which have been taken during routine diagnostic and treatment procedures and tests, from children, teenagers and young adults diagnosed with a solid tumour. Samples may include tumour itself or other tissues including blood and bone marrow.

  CCLG samples are stored initially at the patients' hospitals and then transferred in batches to a Central Bank at Newcastle University for storage until they are released to researchers performing CCLG approved studies.

  The Tissue Bank will store routine clinical and demographic information about patients and their samples, obtained from the patients' healthcare teams. Sometimes additional information is required in order to maximise the usefulness of the samples donated; this may be obtained from the patients' hospitals, from clinical trials units or authorised disease registries. Data is stored at Leicester University.

  Informed consent from patients and/or their parents/guardians will be obtained in writing by appropriately trained staff at the patients' hospitals. All samples used in research are anonymised and given unique codes so researchers use these samples without knowing the patients' personal details.

• Research programme

  Despite improvements in the survival of children, teenagers and young adults with cancer in recent years much remains to be done to help those with difficult to treat tumours and to help reduce the short and long term side effects of treatment. By working to understand how childhood cancers develop and what makes them grow, doctors and scientists aim to improve the prevention, detection and treatment of these conditions. The national CCLG Tissue Bank was set up to support these important studies by providing a Bank of patient samples voluntarily donated for use in research. All researchers from universities, hospitals, charitable organisations and companies, in the UK and abroad, may apply to use tissue samples and associated data from the Tissue Bank for their research projects. These projects include studies into the genetic and biochemical abnormalities driving cancers, ways in which specific cancer types may be detected in the body and new ways of treating cancer. Only research projects which meet stringent scientific standards can use banked samples, in order to ensure that this valuable resource is used as wisely as possible. The results of supported research are publicised so that new findings can help improve future clinical care.

• Storage license

  12534

• RTBTitle

  Children's Cancer and Leukaemia Group (CCLG) Tissue Bank (2018 BS 03)

• Establishment organisation

  Children's Cancer and Leukaemia Group

• Establishment organisation address

  University of Leicester

  Clinical Sciences Building

  Leicester Royal Infirmary, Leicester

  LE2 7LX