Cardiopulmonary resuscitation outcomes in the UK KRT population
Research type
Research Study
Full title
Incidence and outcomes of in-hospital cardiac arrest and cardiopulmonary resuscitation in the United Kingdom kidney replacement therapy population.
IRAS ID
316378
Contact name
Maria Pippias
Contact email
Sponsor organisation
University of Bristol
Duration of Study in the UK
2 years, 0 months, 0 days
Research summary
When a person’s kidneys fail, they may start kidney replacement therapy (KRT) in the form of dialysis or receive a kidney transplant. Although these replace some of the kidneys’ functions, people receiving different forms of KRT are at a higher risk of serious health problems, including sudden death. Cardiopulmonary resuscitation (CPR – heart massage) can prevent death for a small number of people whose heart stops beating (cardiac arrest), but it does not always work, and it may leave people with a poor quality of life.
In order to understand whether patients would want treatments such as CPR, healthcare professionals need to discuss these situations ahead of time. This process is called advance care planning. Several research studies have tried to understand how often cardiac arrest happens in people with kidney failure, how likely they are to survive, and what quality of life they are left with. However, the findings of these studies are not always in agreement with each other and none of them come from the UK. This is a problem, as advance care planning decisions are being made without enough information about survival and quality of life after CPR.
To answer these questions, we have designed a study that plans to look back at data in people receiving KRT between 2012 and 2022. A healthcare registry collects information on people with the same diagnosis, treatment, or outcome. We will combine information from two registries, and using statistical analysis, we will describe how often people receiving KRT have a cardiac arrest when in hospital. We will also describe how many people receiving KRT have survived a cardiac rest after receiving CPR, how long they live for and what quality of life they have after surviving a cardiac arrest.
REC name
South West - Cornwall & Plymouth Research Ethics Committee
REC reference
24/SW/0075
Date of REC Opinion
26 Jun 2024
REC opinion
Favourable Opinion