Cardiff School of Dentistry Tooth Bank

• Research type

  Research Tissue Bank

• IRAS ID

  238792

• Research summary

  Cardiff School of Dentistry Tooth Bank

• REC name

  Wales REC 1

• REC reference

  17/WA/0405

• Date of REC Opinion

  7 Dec 2017

• REC opinion

  Favourable Opinion

• Data collection arrangements

  Teeth due for extraction, referred as requiring the extraction of teeth by clinical staff in the University Dental Hospital, Cardiff will be collected from various dental clinics within Cardiff and Vale Trust and stored as part of a Tooth Bank forresearch purposes. Information sheets will be given to potential donors on the day treatment is planned. Patients requiring further information will be able to contact one of the named researchers named on the information sheet. Written consent will be obtained by the dental surgeon immediately prior to extraction. Teeth are normally treated as waste material within the clinic and Hospital policy does not encourage patients to take away extracted teeth for health and safety reasons. If patients are unable to make decisions prior to surgery their teeth will not be entered into the
  Tooth Bank. Teeth will be anonymised and the only information available to researchers will be tooth type, 10 year age range and whether dental decay or a dental filling are present. It will be impossible to retrace the tooth back to the
  patient donor if consent is withdrawn and this is stated in patient information sheet.

• Research programme

  The overall aim of the “Tooth Bank” is to provide researchers within the School of Dentistry with tissue samples which will be utilised in translational research, through providing better understanding of disease mechanisms, promoting mineralised tissue repair, improving the efficacy of therapeutic and clinical developments, and thus facilitating better chairside care. Teeth will be utilised for the testing of new dental materials, instruments and devices which come into contact with teeth; to evaluate how they interact with the tooth and influence tooth surface and structure with a long term aim of improving longevity of dental restorations. In addition studies aim to improve dental treatments by assessing novel medicine and antimicrobials placed in the pulpal cavity with a view to improving efficiency in reducing pulpal infections. Complementary to this, research within the School of Dentistry is taking a biological approach to dental care. Studies are identifying bioactive components within the tooth matrix and looking at a variety of approaches to exploit these components to enhance the cells within teeth and bones towards promoting natural repair processes.

• Storage license

  12422

• RTBTitle

  Cardiff School of Dentistry Tooth Bank

• Establishment organisation

  School of Dentistry

• Establishment organisation address

  Cardiff University

  Heath Park

  Cardiff

  CF14 4XY