CARAMEL

  • Research type

    Research Study

  • Full title

    Cardiorespiratory Markers Inferred from Photoplethysmography Using Machine Learning - CARAMEL

  • IRAS ID

    325931

  • Contact name

    Elina Naydenova

  • Contact email

    elina@feebris.com

  • Sponsor organisation

    Feebris Ltd

  • Duration of Study in the UK

    0 years, 11 months, 26 days

  • Research summary

    This research study protocol aims to explore the use of algorithms for extracting reliable information from pulse oximeter devices and digital stethoscopes. The study focuses on deriving breathing rate (BR), pulse rate (PR) and detecting heart rhythm abnormalities, including indicators of atrial fibrillation (AF), from pulse oximetry signals. The study will take place in community settings such as the sponsor offices. It is non-interventional and involves negligible participant risk. Data will be collected from up to 200 participants (data collection: ~20 minutes per person). Participants will be above 18 years of age, and acutely well at the time of the study. Participants will undergo breathing rate/sound and pulse rate measurements using pulse oximeters, a digital stethoscope and capnography (a measurement of exhaled carbon-dioxide, and therefore breathing frequency). For heart rhythm abnormalities, participants will wear pulse oximeters and ECG leads. The study aims to investigate scalable and cost-effective methods for deriving important information about a patient’s clinical status from pulse oximeter devices and a digital stethoscope.

  • REC name

    South Central - Oxford C Research Ethics Committee

  • REC reference

    23/SC/0146

  • Date of REC Opinion

    3 Aug 2023

  • REC opinion

    Further Information Favourable Opinion