CAPO Study
Research type
Research Study
Full title
Cerebrovascular accident and Acute coronary syndrome and Peri-operative Outcomes Study
IRAS ID
256104
Contact name
Iain K Moppett
Contact email
Sponsor organisation
University of Nottingham
Duration of Study in the UK
3 years, months, days
Research summary
A previous stroke or heart attack is associated with increased risk of worse outcomes after surgery. These outcomes include death, having a stroke or heart attack soon after surgery, staying in hospital longer than normal and having to be readmitted to hospital after discharge home. We don’t know how these risks are affected by the length of time between having a stroke or heart attack and having an operation, the type of surgery, or the type of stroke or heart attack. A better understanding of this would enable a more informed discussions between surgeons, anaesthetists and patients about the most appropriate treatment plan. For example, if there is a high risk in the first few months, then delaying surgery might be in a patient’s interest. On the other hand, if there is a time after which risks do not decrease any more then there is probably little point in delaying surgery beyond this.
We plan to study information from three databases about patients in England. The Hospital Episode Statistics (HES) dataset is a comprehensive database of admissions to hospital with information about operations, current and previous diagnoses. The Sentinel Stoke National Audit Programme (SSNAP) records information about people who have stroke and the Myocardial Ischaemia National Audit Project (MINAP) records information about people who have heart attacks. We will look at people who had surgery between 2007 and 2017 and link this to information about previous strokes or heart attacks.
At the end of the study we hope to be able to provide better information to patients, doctors, other healthcare professionals and researchers about the risks around the time of surgery for people who have had strokes or heart attacks previously. We hope to be able to provide accurate information that is specific to the type of surgery patients are having.
REC name
East Midlands - Nottingham 1 Research Ethics Committee
REC reference
18/EM/0403
Date of REC Opinion
19 Dec 2018
REC opinion
Favourable Opinion