Cancer related fatigue in HANC and the role of physical activity
Research type
Research Study
Full title
Longitudinal investigation of cancer related fatigue in head and neck cancer with an emphasis on the role of physical activity
IRAS ID
308808
Contact name
Prahalad Narasimhan
Contact email
Sponsor organisation
Edge Hill University
Clinicaltrials.gov Identifier
ETH2122-0010, Edge Hill University Health Research Ethics Committee Approval
Duration of Study in the UK
1 years, 7 months, 28 days
Research summary
Background:
Cancer related fatigue is multifactorial in nature with physiological, psychological and treatment associated causes, some of which cause irreversible tissue damage. Cancer related fatigue is also not a constant phenomenon, demonstrated by the varying levels of fatigue in patients on a daily basis. It is therefore important to identify the trajectory and impact of fatigue to better provide supportive care or rehabilitation interventions. Physical activity can make positive adjustments to fatigue and significantly impact on health related quality of life (HRQOL). However physical activity can be a challenge for patients following head and neck cancer treatment for many reasons, with fatigue an important limiting factor.
Thus a longitudinal investigation will be conducted to better understand the symptom of fatigue and its impact on physical activity as well as health related quality of life. The findings from the study may improve how rehabilitation interventions for head and neck cancers are planned and delivered to the patients/survivors.Methods:
> 12 month cohort observation (head and neck cancer) from the time of diagnosis
> Assessment of changes in fatigue, physical activity, cardiorespiratory fitness, functional capacity, haemoglobin, blood counts, thyroid function, inflammation levels, body mass, body composition and sleep quality over 12 months
> Interviews to understand the participant's lived experiences of fatigue and its impact on their physical activity participation.Dissemination of results:
The results of the research will be presented at conferences and published in scientific journals. A lay summary of the results may also be provided to participants via email on request.REC name
Yorkshire & The Humber - Leeds West Research Ethics Committee
REC reference
22/YH/0126
Date of REC Opinion
18 Jul 2022
REC opinion
Further Information Favourable Opinion