Can we use c-SIGHT for spatial neglect in stroke survivor’s homes?
Research type
Research Study
Full title
A feasibility study of a computerised Spatial Inattention Grasping Home-based Therapy for stroke survivors (c-SIGHT)
IRAS ID
275001
Contact name
Stephanie Rossit
Contact email
Sponsor organisation
University of East Anglia
Clinicaltrials.gov Identifier
Duration of Study in the UK
3 years, 4 months, 31 days
Research summary
Spatial neglect is a common post-stroke condition, meaning people may not be aware of anything on one side. Currently, there is no effective treatment and widely used paper-and-pencil tests often under diagnose spatial neglect. Here, we will test if a new computerised therapy for neglect (c-SIGHT; computerised Spatial Inattention Grasping Home-based Therapy) can be self-administered at home, and how to carry out a large-scale clinical trial (Study 1). We will also test the accuracy of a new computerised spatial neglect test (CENT; computerised extrapersonal neglect test) compared to paper-and-pencil tests (Study 2). We will recruit 92 stroke survivors from clinical sites in the East of England (46 with spatial neglect for Study 1, and 46 without any signs of spatial neglect for Study 2). Like Study 1, Study 2 will involve stroke survivors completing a series of tests measuring spatial neglect, cognition, vision, sensorimotor function, activities of daily living, and questionnaires measuring mood, fatigue and the impact of their stroke, on one visit. Stroke survivors in Study 1 will be randomly allocated to either c-SIGHT 1 (intervention) or c-SIGHT 2 (attentional control) group. Both groups will use c-SIGHT for 30 minutes, twice a day for 10 days independently at home. Stroke survivors will complete the tasks outlined above, before, after and one-month after using c-SIGHT. Carers of stroke survivors in Study 1 will be invited to complete questionnaires throughout the trial, and take part in a short interview with the stroke survivor after using c-SIGHT. It is hoped that this research will provide a home-based and self-administered therapy for stroke survivors with spatial neglect at home and a more sensitive test to detect this severe condition. This project is led by researchers at the University of East Anglia and funded by the Stroke Association.
REC name
East of England - Cambridge South Research Ethics Committee
REC reference
20/EE/0107
Date of REC Opinion
9 Jun 2020
REC opinion
Further Information Favourable Opinion