Can surface roughness predict progression of tooth wear?
Research type
Research Study
Full title
Can surface roughness predict progression of tooth wear in patients with dietary origins of acid? An in situ study
IRAS ID
166841
Contact name
David Barteltt
Contact email
Sponsor organisation
KCL
Duration of Study in the UK
0 years, 6 months, 29 days
Research summary
The aim of this study is to investigate if exposure to a dietary acid ( orange juice) causes reversible but short term changes to the surface texture of tooth enamel. The aim is to quantify and analyse the surface of enamel using imaging techniques and to identify if this marker of tooth wear can act as a predictor for progression.
Potential participants will be recruited from consultant led tooth wear clinics at Guy’s dental Schoo. Participation in the study will in no way influence care they receive.
Patients consenting to participate will have custom made mouth splints for them to wear (similar to orthodontic braces or sports mouth guards). These splints will contain samples of tooth enamel and will be worn whilst the patient rinses their mouth with orange juice. At the same time other enamel samples will be immersed in orange juice outside the mouth for the same time duration.
All the sterilised enamel samples will then be examined using a high precision laser and surface texture measurements of the enamel will be scrutinized.
The results of this study will help aid identification of early surface markers of tooth wear and be useful to help develop new methods of prevention and treatment of tooth wear.REC name
London - Stanmore Research Ethics Committee
REC reference
15/LO/0417
Date of REC Opinion
9 Jun 2015
REC opinion
Further Information Favourable Opinion