Calcium Phosphate Crystal Screening for Aortic Stenosis Pilot Study

• Research type

  Research Study

• Full title

  Calcium Phosphate Crystal Screening for Aortic Stenosis Case-Control Pilot Study

• IRAS ID

  186477

• Contact name

  D Wald

• Contact email

  d.s.wald@qmul.ac.uk

• Sponsor organisation

  Barts Health NHS Trust

• Duration of Study in the UK

  1 years, 3 months, 0 days

• Research summary

  A case – control pilot study will be conducted. Patients with echocardiographically confirmed aortic stenosis will be identified from echocardiography clinics and cardiology wards. Blood will be collected and assayed for the presence and concentration of calcium phosphate particles by scanning electron microscopy methods, together with serum for calcium and phosphate measured by standard laboratory techniques. Blood samples from subjects without aortic stenosis, identified from individuals having echocardiography for other reasons, will also be collected for the same analyses.

• REC name

  North West - Preston Research Ethics Committee

• REC reference

  15/NW/0940

• Date of REC Opinion

  1 Dec 2015

• REC opinion

  Favourable Opinion