C2N Study. SCS Conversion to Novel Waveform Study.
Research type
Research Study
Full title
C2N Study. SCS Conversion to Novel Waveform Study.
IRAS ID
342022
Contact name
GIRISH VAJRAMANI
Contact email
Sponsor organisation
University Hospital Southampton NHS Foundation Trust
Duration of Study in the UK
1 years, 6 months, 30 days
Research summary
Spinal cord stimulation is effective and established therapy in treatment of chronic pain. However in the long term, a decrease in the effectiveness of SCS therapy can be observed, leading to loss of efficacy and ultimately system explant. A failed spinal cord stimulator can be salvaged by converting it to a different waveform. Previous studies have shown that a multi channel spinal cord stimulator device capable of improved neural targeting can salvage patients who have either loss of coverage or loss of efficacy from the current Spinal Cord Stimulator device Furthermore newer waveform such as FAST -fast acting suppression therapy- may provide a useful additional tool for salvage therapy.
In this study hope to establish the efficacy of both neural targeting algorithm and novel FAST waveform in restoring the benefits of spinal cord stimulator in refractory patients
REC name
South Central - Hampshire A Research Ethics Committee
REC reference
25/SC/0189
Date of REC Opinion
13 Oct 2025
REC opinion
Further Information Favourable Opinion