C-MABQ Survey v1.0

• Research type

  Research Study

• Full title

  Collaborative Medication Adherence in Bipolar disorder Questionnaire (C-MABQ) Survey

• IRAS ID

  297357

• Contact name

  Asta Ratna Prajapati

• Contact email

  asta.prajapati@nsft.nhs.uk

• Sponsor organisation

  Norfolk and Suffolk NHS Foundation Trust

• Duration of Study in the UK

  0 years, 9 months, 18 days

• Research summary

  An estimated 40% of patients with bipolar disorder do not take their medication as prescribed. This medication non-adherence is associated with relapse, functional impairment, increased risk of hospitalisation and suicidality. For example, the probability of hospitalisation is five times higher in non-adherent patients with bipolar disorder. Clinicians need to understand what helps and hinders individual patients from taking their medication so that patients and clinicians can work together to find the most suitable solution.

  We recently developed a medication adherence questionnaire called “Collaborative Medication Adherence in Bipolar disorder Questionnaire (C-MABQ)”. The process for development of C-MABQ is briefly summarised below:
  1. First, we looked at the literature to identify what helps and hinders people from taking their medication in bipolar disorder.
  2. We then spoke to patients with bipolar disorder and their family and friends to check what we found in the literature make sense to them. We also ask them if there are any other issues that might help or hinder taking medication that have not been mentioned in the literature.
  3. And finally, we consulted with psychiatrists, pharmacists, nurses, psychologists, medication adherence experts and patients.

  C-MABQ will not only identify patients who struggle to take their medications as prescribed but also identify their unique difficulties. We believe that this C-MABQ will help clinicians to provide patient centred support. But before using C-MABQ in clinical practice, we need to test them and refine the C-MABQ if needed. In this study, we plan to test the C-MABQ with around 600 patients with bipolar disorder. We will ask patients (via email and post) to complete C-MABQ survey (on paper or online) which will take around 20-30 minutes. We plan to recruit these patients from Norfolk and Suffolk NHS Foundation Trust in England.
  

• REC name

  South West - Central Bristol Research Ethics Committee

• REC reference

  21/SW/0078

• Date of REC Opinion

  17 Jun 2021

• REC opinion

  Further Information Favourable Opinion