C-LACE: Cefuroxime Levels After Caesarean Section

• Research type

  Research Study

• Full title

  Understanding pharmacokinetic distribution of cefuroxime when given prior to Caesarean section in body fat and blood

• IRAS ID

  244803

• Contact name

  Victoria Hodgetts Morton

• Contact email

  v.a.h.morton@bham.ac.uk

• Sponsor organisation

  University of Birmingham

• Duration of Study in the UK

  1 years, 3 months, 25 days

• Research summary

  This study will evaluate the concentration of Cefuroxime in stomach adipose tissue and blood from pregnant women undergoing a scheduled Caesarean section. Analysis will explore the impact of BMI (body mass index) vs dose of cefuroxime on the concentrations of drug determined. The study participants will be followed up between 30 and 40 days post C-section to record details of any post-caesarean infection to explore correlations in BMI:measured cefuroxime concentrations and post caesarean infection rates.

• REC name

  East Midlands - Leicester Central Research Ethics Committee

• REC reference

  19/EM/0356

• Date of REC Opinion

  18 Dec 2019

• REC opinion

  Favourable Opinion