Burns Wound Dressing Volatile Compounds - follow on study (DRESSVOCS2)
Research type
Research Study
Full title
Rapid diagnosis of wound infection via the detection of microbial volatiles from discarded patient wound dressing material; a proof of principle study
IRAS ID
172069
Contact name
Amber ER Young
Contact email
Sponsor organisation
University Hopsital Bristol NHS Foundation Trust
Duration of Study in the UK
0 years, 11 months, 30 days
Research summary
Study will look at the gases released from wound dressings used to treat adults and children with burn injuries as a method of detecting wound infection. The findings will inform a future study to develop a point of care bedside device for burn wound infection detection. For this study we will be asking patients and parents of children with burns if we can send their used wound dressings to a university laboratory. They will be enclosed in air-tight bags and transported to the university, where the gas emanating from the dressing samples will be analysed using a machine capable of differentiating compounds (smells) which indicate the presence of bacteria. The dressings, which would have been discarded in a clinical waste bin, will be placed in a clear bag and sealed. The bag will be securely stored until transferred to the University. Patient details will be collected including: age, gender, ethnic origin, date of injury, cause of injury, type of burn (scald, flame, contact), depth of burn, date and time the dressing was removed, type of dressing, location of the burn on the body, and clinical signs of infection including wound picture. This data will only be able to be linked back to the patient with a unique study identification number. This will be securely stored in the site file at the clinical study sites. If as a part of the patient's routine treatment there is a requirement for blood tests and wound swabs, these tests will be linked back anonymously to the study findings.
REC name
Yorkshire & The Humber - Leeds East Research Ethics Committee
REC reference
15/YH/0304
Date of REC Opinion
29 Jun 2015
REC opinion
Favourable Opinion