BRICE
Research type
Research Study
Full title
Burden of RSV Infection in young Children in European countries (BRICE study)
IRAS ID
294308
Contact name
Atul Gupta
Contact email
Sponsor organisation
Merck Sharp & Dohme Corp
Duration of Study in the UK
2 years, 4 months, 31 days
Research summary
This is a multi center, international, prospective, observational study of children ≤2 years of age who have been hospitalized with Respiratory Syncytial Virus (RSV). The aim of the study is to estimate the population based incidence rate of RSV hospitalization and to understand the burdens associated of RSV.
The study will be comprised of two parts: A total 200 participants per country will be enrolled in the RSV Hospitalization Impact Survey Study and approximately 100 enrolled per country for the Wheezing Follow Up Study.
The study will be conducted in the United Kingdom, France, Germany, Spain and Italy with 1 NHS site in England.
The total study duration will be from October 2020 to May 2023. Enrolment will occur from October 2020 to May 2022 during two RSV seasons. There will be a 12 month follow up period which will end in May 2023
REC name
London - Brighton & Sussex Research Ethics Committee
REC reference
21/PR/0095
Date of REC Opinion
15 Feb 2021
REC opinion
Unfavourable Opinion