BRICE

  • Research type

    Research Study

  • Full title

    Burden of RSV Infection in young Children in European countries (BRICE study)

  • IRAS ID

    303382

  • Contact name

    Atul Gupta

  • Contact email

    atulgupta1@nhs.net

  • Sponsor organisation

    Merck Sharp & Dohme Corp

  • Duration of Study in the UK

    2 years, 1 months, 17 days

  • Research summary

    This is a multi center, international, prospective, observational study of children ≤2 years of age who have been hospitalized with Respiratory Syncytial Virus (RSV). The aim of the study is to estimate the population based incidence rate of RSV hospitalization and to understand the burdens associated of RSV.

    The study will be comprised of two parts: A total 200 participants per country will be enrolled in the RSV Hospitalization Impact Survey Study and approximately 100 enrolled per country for the Wheezing Follow Up Study.

    The study will be conducted in the United Kingdom, France, Germany, Spain and Italy with 1 NHS site in England.

    Enrollment: two RSV seasons between 2020 and 2022 (typically occurs between October and March). 12-month follow-up periods after discharge

  • REC name

    London - Brighton & Sussex Research Ethics Committee

  • REC reference

    21/LO/0578

  • Date of REC Opinion

    26 Nov 2021

  • REC opinion

    Further Information Favourable Opinion