Brain Tumors, Seizures and Electroencephalography: A Pilot Study.
Research type
Research Study
Full title
Brain Tumors, Seizures and Electroencephalography. A Pilot Study.
IRAS ID
327176
Contact name
Elisaveta Sokolov
Contact email
Sponsor organisation
Guy’s and St Thomas’ NHS Foundation Trust
Clinicaltrials.gov Identifier
N/A, N/A
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
Seizures are amongst the most common clinical symptom associated with brain tumours and the bi-directionality of this integral relationship is emerging. Recent advances have enabled understanding as to why some of these patients are susceptible to seizures, how these manifest, and what implications seizures have for patient management.
The area being studied is epilepsy in the setting of brain tumour patients. The service being utilised is a neurophysiology service, EEG.
Any patient with a new diagnosis of glioma 18 years or older can be included in this pilot study. Patients who lack the ability to consent to the study or who have a different type of brain tumour, or who have a former diagnosis of epilepsy or indeed previous seizures, will be excluded.
The study will be conducted at St Thomas Hospital, London. The study will be one year in duration with patients undergoing a sleep deprived EEG study at time zero and then again at the eight month interval.Here we consider whether electroencephalogram study (EEG) performed at the time of new glioma diagnosis, in seizure free patients, can inform us of epileptic discharge burden. This project is the first step to understanding this question. This is relevant to patients as ultimately may lead to them being managed more efficiently, with less side-effects and less unnecessary medications.
REC name
East Midlands - Derby Research Ethics Committee
REC reference
24/EM/0175
Date of REC Opinion
22 Aug 2024
REC opinion
Further Information Favourable Opinion