BRAIN fMRI study (Body Relations Agency and Image Network) v1.0

  • Research type

    Research Study

  • Full title

    Neural and behavioural correlates of disordered agency and body image in relational disorder

  • IRAS ID

    274202

  • Contact name

    Susan Mizen

  • Contact email

    susanmizen@nhs.net

  • Sponsor organisation

    Exeter University

  • Duration of Study in the UK

    2 years, 10 months, 31 days

  • Research summary

    Do unconscious (implicit) psychological conflicts in relationships give rise to psychological symptoms and are specific symptoms associated with distinct ways of relating to others? This question is important because the detail of the interpersonal stressors which contribute to the development of mental health problems is poorly understood. Understanding these mechanisms may promote more refined psychological approaches to complex mental health problems.

    The BRAIN fMRI study is a behavioural experiment and fMRI (Functional Magnetic Resonance Imaging) study of psychiatric patients with either restricting eating disorders or functional movement disorders arising from underlying relational disorder (Personality Disorder) and healthy volunteer control participants. The patients will be current service users from Devon Partnership NHS Trust and the control participants will be recruited from students and staff at the University of Exeter.

    Following screening to exclude mental health problems (control group) and a meeting to obtain informed consent and put a risk assessment and recovery plan in place (patient group) all participants will be invited to attend two study days.

    On the first day participants will undertake a video recorded psycho-therapeutic interview, diagnostic interview and a series of psychological tests. These will be scored and rated and the data used to inform the second test day. On the second day participants will undertake further audio recorded narrative interviews to elicit individual emotional response data and a behavioural experiment measuring emotional egocentricity bias before undergoing two fMRI brain scans. The first scan involves recalling narratives on cue from a picture set, the second scan involves participation in a virtual ball throwing game.

  • REC name

    London - Fulham Research Ethics Committee

  • REC reference

    20/PR/0040

  • Date of REC Opinion

    31 Jul 2020

  • REC opinion

    Further Information Favourable Opinion