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BOSU Study on Essential Infantile Esotropia

  • Research type

    Research Study

  • Full title

    The incidence, presentation, treatment, and motor outcomes of essential infantile esotropia in the UK



  • Contact name

    Patrick Watts

  • Contact email

  • Sponsor organisation

    Cardiff and Vale University Health Board

  • Duration of Study in the UK

    1 years, 6 months, 2 days

  • Research summary

    Essential infantile esotropia or congenital esotropia is a large angle non accommodative squint which develops within the first six months of life. The reported incidence from population studies in the USA suggests an incidence of 1 in 403 live births. In the UK with 695,233 live births in 2014 this would equate to an incidence of 1725 cases annually. A hospital with a live birth rate in between 6000 to 10000 would expect to see about 15 to 25 cases per year. This does not appear to mirror the clinical experience in most ophthalmology departments in the UK where congenital esotropia is rare or there appears to be a decreasing trend in its presentation.
    In the UK, there is no data reporting current practice of the timing of surgery or the motor or binocular outcomes of surgery undertaken within the first year of life. We aim to determine the number of incident cases of congenital esotropia, its presentation, treatment choice, and early motor outcomes of cases presenting to ophthalmologists in the UK through a prospective observational study of cases of congenital esotropia reported through the British Ophthalmic Surveillance Unit reporting card system.

  • REC name

    East Midlands - Leicester South Research Ethics Committee

  • REC reference


  • Date of REC Opinion

    10 Mar 2017

  • REC opinion

    Favourable Opinion