Boston-London-Toronto Rare Cerebrovascular Disease Consortium
Research type
Research Study
Full title
Boston-London-Toronto Rare Cerebrovascular Disease Consortium
IRAS ID
322266
Contact name
Greg James
Contact email
Sponsor organisation
Boston Children's Hospital
Duration of Study in the UK
10 years, 0 months, 1 days
Research summary
We aim to create a consortium between the Boston Children's Hospital, SickKids Hospital of Toronto, and Great Ormond Street Hospital of London. The purpose of this consortium is to collect data on children presenting with cerebrovascular diseases that are rare. Since these diseases are rare, individual institutions will
not encounter significant numbers of patients over time to fully understand the determinants of a favorable or unfavorable prognosis. By using a software called ChRIS, these institutions will upload de-identified medical records and images to share with each other. The research teams at the institutions will then use this dataset to try and determine better treatment options for patients, by searching for trends within the greater dataset. The dataset, through ChRIS, will be housed under BCH, and therefore BCH will be the main site. In an effort to not limit the dataset, this consortium will be open to other institutions with patients that meet inclusion criteria. In the event that another institution would like to contribute to the consortium, we will submit an amendment to add the site and execute a DUA and/or MTA. Additionally, Boston Children's Hospital will be accepting samples from outside institutions. This will allow Boston Children's to be a central lab for the institutions to send clinically interesting samples (blood, urine, brain tissue, bone, stool...etc) to be analyzed.REC name
West of Scotland REC 5
REC reference
25/WS/0065
Date of REC Opinion
3 Jul 2025
REC opinion
Further Information Favourable Opinion