Body composition in older adults (BODI Study)
Research type
Research Study
Full title
An exploration of body composition in older adults undergoing systemic anticancer treatment.
IRAS ID
345668
Contact name
Megan Pattwell
Contact email
Sponsor organisation
Royal Marsden NHS Foundation Trust
Clinicaltrials.gov Identifier
Clinicaltrials.gov Identifier
NCT06630754, Clinical Trials.gov
Duration of Study in the UK
0 years, 6 months, 30 days
Research summary
The name of the study is: An exploration of body composition in older adults undergoing systemic anticancer treatment.
The primary aim of the study is to explore body composition (the fat, muscle and water content of someone's body) in older adults (aged 70 years and over) with cancer, undergoing systemic anticancer treatment (e.g., chemotherapy). Additional aims include to explore the extent of body composition changes and whether changes are tumour specific, the incidence for cancer-related cachexia and sarcopenia (muscle +/- fat wasting conditions) and finally, how body composition can inform nutritional management of older adults with cancer.
To do this, I have applied for and been awarded funding to pay for a part time band 4 (or equivalent) to take monthly body composition measures on the patients who are eligible and accepting of assessment by a team specialising in oncology care for older adults, and consent to these measures. Measurements will include an analysis from the Bioelectrical Impedance Analysis (BIA) machine which measures the fat, lean muscle, and water content in the body; waist to hip ratio; handgrip strength; calf circumferences. Socio-demographic data (such as age, cancer diagnosis) will also be collected.
I intend to descriptively analyse this data to explore possible trends and associations which may inform future research and drive even further personalised care for this growing and typically underrepresented in research, population.
REC name
North West - Greater Manchester South Research Ethics Committee
REC reference
24/NW/0387
Date of REC Opinion
20 Dec 2024
REC opinion
Favourable Opinion