Blood Microvesicles
Research type
Research Study
Full title
Characterising microvesicles and their function in the dynamics of thrombus formation, cell interaction and inflammation.
IRAS ID
172734
Contact name
Nicola Englyst
Contact email
Duration of Study in the UK
5 years, 8 months, 0 days
Research summary
Microvesicles are small membrane particles released by cells when they are activated. This research will assess the role of microvesicles in 1) blood clotting, 2) cell interactions, and 3) inflammation and cell activation. In addition, this research will examine 4) the role of nucleic acids in microvesicles, 5) the role of membrane lipids and proteins in microvesicles, and 6) how microvesicles are formed.
Blood samples will be taken in Southampton General Hospital (SGH) by Giedo Elamin who is an experienced phlebotomist or someone else experienced in phlebotomy. Laboratory work will be carried out predominantly in the Institute of Developmental Sciences, but also in University Laboratories in SGH and at Highfield.
Volunteers will be healthy fellow students and staff at SGH and UoS, and any healthy adult who wishes to volunteer, aged 18 to 60 years.
REC name
South West - Cornwall & Plymouth Research Ethics Committee
REC reference
15/SW/0258
Date of REC Opinion
25 Aug 2015
REC opinion
Favourable Opinion