Blood cell mutation analysis in pancreatic disease v1

  • Research type

    Research Study

  • Full title

    An investigation of the utility of a blood cell mutation test in diagnosing early pancreatic cancer.

  • IRAS ID

    218936

  • Contact name

    Lucy Nichols

  • Contact email

    786460@swansea.ac.uk

  • Duration of Study in the UK

    2 years, 11 months, 31 days

  • Research summary

    We are interested in developing novel blood tests to detect the presence of cancer at an early stage. We have optimised a blood based cancer test in oesophageal cancer, we would like to test its performance with pancreatic cancer.
    Our test measures blood cell mutations, we have shown cancer patients have more mutated cells than non-cancer patients. We would like to answer the following question:
    Do pancreatic cancer patients have more blood cell mutations than non-cancer controls.

    As well as blood, we would like to later access the biopsy material collected for routine clinical purposes to compare mutation in the pancreatic tissue to that in the blood cells (no additional biopsies collected).

  • REC name

    South West - Cornwall & Plymouth Research Ethics Committee

  • REC reference

    17/SW/0012

  • Date of REC Opinion

    25 Jan 2017

  • REC opinion

    Further Information Favourable Opinion