BISCUIT

  • Research type

    Research Study

  • Full title

    Brain Injury, Sleep and Cognition – Untangling to the long-term impact of childhood TBI

  • IRAS ID

    346901

  • Contact name

    Bosiljka Milosavljevic

  • Contact email

    b.milosavljevic@qmul.ac.uk

  • Sponsor organisation

    Queen Mary University of London

  • Duration of Study in the UK

    1 years, 5 months, 30 days

  • Research summary

    Head injuries are very common during childhood, particularly in babies and
    teenagers. Children often make a full recovery from a head injury but sometimes
    behaviour problems and learning issues may follow. Understanding when and why
    that happens is important. Even more critical is the need to explore if there is
    anything we can change in the child’s everyday routine to minimize such problems.
    Past studies have shown that sleep may be disrupted following a head injury. Given
    the established link between sleep and school performance as well as conduct
    problems, we want to study sleep quality in this population and comprehend how
    sleep problems contribute to thinking skills and behaviour. We also want to find out
    which sleep interventions families would be most happy to use. We will be collecting
    data from children aged one month to 16 years who were seen at the Royal London
    Hospital and classified as having a significant head injury. We will be using activity
    tracking devices and parental questionnaires to evaluate sleep. In addition, we will
    assess general intelligence and behaviour using measurement tools that have been
    used extensively with children. Finally, we will develop a questionnaire asking
    questions related to the type of sleep interventions families would be willing to
    implement. A subset of families will also take part in an online focus group to explore
    their opinions in more depth. We believe that the current study will give us important
    insights into the relationship between sleep and functioning. Most past studies
    haven’t used objective measures and there are very few studies investigating sleep in
    babies following a head injury. What’s more, our study will give parents and older
    children the chance to provide valuable input for the design of a sleep intervention.

  • REC name

    London - Riverside Research Ethics Committee

  • REC reference

    25/LO/0557

  • Date of REC Opinion

    16 Sep 2025

  • REC opinion

    Further Information Favourable Opinion