Biomedical Research Unit (BRU) Respiratory Biobank
Research type
Research Tissue Bank
IRAS ID
155542
Contact name
Tracy Higgins
Contact email
Research summary
Biomedical Research Unit (BRU) Respiratory Biobank
REC name
South Central - Hampshire B Research Ethics Committee
REC reference
15/SC/0101
Date of REC Opinion
11 Mar 2015
REC opinion
Favourable Opinion
Data collection arrangements
Patients attending the hospital for procedures will be approached by fully trained staff members in order to ask if they would like to participate in donating samples to the BRU biobank. The consent form will be accompanied by an information leaflet that will explain the details of the biobank and purpose for collecting samples and data. If a patient consents for research they will provide us with samples and details which will be recorded within the Trust database and have restricted access. Samples will include (1) Urine (2) Stool (3) Exhaled Breath Condensate (4) Cough swabs, throat swabs and nasal swabs (5) Nasopharygeal Aspirate (6) Sputum (spontaneous or induced) (7) Blood (8) Bronchial brushings (9) nasal brushings (10) Bronchoalveolar Lavage (BAL (11) Bronchial biopsies (12) Nasal biopsies (13) Resected lung related vasculature and nerves (14) Transplant tissue (recipient explant)
The tissue samples will be stored within the secure Trust laboratories before being transferred to a secure off site facility run by Fisher Bioscience.
The patients data will remain securely stored within the gated security Trust database - Labvantage.
Research programme
Samples and data will be available to researchers from hospitals, academia and commercial industry who are conducting research into lung disease. The BRU Respiratory Biobank will provide samples and data to translational medical research projects in lung disease. The BRU Respiratory Biobank's main objective is to increase the rate at which clinically beneficial treatments are developed for patients with lung diseases. This will be done by (i) increasing the availability of tissue for research and (ii) bringing together leading scientists, clinicians and patients advocates to assess projects and prioritise studies. The BRU Respiratory Biobank will be publicised on the Trust website (http://www.rbht.nhs.uk/research/brus/) which will have a range of useful information such as details of the application process. The tissue bank will also be publicised in hospital newsletters, on the NIHR Experimental Medicine website(www.ukcrn.org.uk/index/clinical/experimental.html), through networking at scientific meetings and through acknowledgements on publications, presentations and posters.
Storage license
12388
RTBTitle
Biomedical Research Unit (BRU) Respiratory Biobank
Establishment organisation
Royal Brompton and Harefield NHS Foundation Trust
Establishment organisation address
Respiratory Biomedical Reserach Unit
Sydney Street
London
SW3 6NP