Biomarkers of Shoulder Pathologies
Research type
Research Study
Full title
Biomarkers of Shoulder Pathologies in Synovial Fluid
IRAS ID
263411
Contact name
Leela Biant
Contact email
Sponsor organisation
University of Manchester
Clinicaltrials.gov Identifier
N/A, N/A
Duration of Study in the UK
1 years, 0 months, 0 days
Research summary
Around 2-5% of people with shoulder pain are diagnosed with frozen shoulder. A frozen shoulder is painful and stiff, meaning that people with the condition often cannot use their shoulder. These symptoms can come and go over the course of months and years. As frozen shoulder can come and go, doctors find it difficult to estimate for how long it will last. This also means it is difficult for doctors to know which treatment would work best, leaving many in long term pain and disability.
This study will aim to find 'biomarkers' of frozen shoulder. A biomarker is something that can be measured in the human body and used to determine level of health or disease. In this study, we will be looking at what proteins are present in shoulder fluid, in the hope to find protein biomarkers.
To find protein biomarkers of frozen shoulder, we will need to collect joint fluid from patients with shoulder problems which are not frozen shoulder as well as from patients with frozen shoulder. The proteins present in the fluids from both groups will then be compared.
If we are able to find protein biomarkers of frozen shoulder in this study, it could lead to better diagnosis and treatment for this condition in future.
REC name
North West - Greater Manchester East Research Ethics Committee
REC reference
19/NW/0393
Date of REC Opinion
4 Jul 2019
REC opinion
Favourable Opinion