BIOCRYPT - Version 1
Research type
Research Study
Full title
Determination of relative bioavailability, bioconversion and bioefficacy of β-cryptoxanthin in comparison to β-carotene from biofortified maize and external stable isotopes using compartmental modelling
IRAS ID
270816
Contact name
Georg Lietz
Contact email
Sponsor organisation
Newcastle University
Clinicaltrials.gov Identifier
Duration of Study in the UK
0 years, 7 months, 31 days
Research summary
Since no quantitative information currently exists on how effectively the pro-vitamin A carotenoid β-cryptoxanthin is converted to vitamin A in humans, this proof of principle study aims to compare the efficacy of both β-cryptoxanthin and β-carotene to yield vitamin A from biofortified maize. This data is critical before the breeding strategy for biofortified maize is directed towards high β-cryptoxanthin-containing varieties in order to reduce vitamin A deficiency in low- and middle-income countries.
REC name
North West - Greater Manchester East Research Ethics Committee
REC reference
22/NW/0046
Date of REC Opinion
20 Apr 2022
REC opinion
Further Information Favourable Opinion