Bespoke vs Standard Instrumentation in TKR
Research type
Research Study
Full title
Randomised controlled trial of patient-specific instrumentation vs standard instrumentation in total knee arthroplasty
IRAS ID
166681
Contact name
Leela Biant
Contact email
Sponsor organisation
Research and Development Department
Duration of Study in the UK
4 years, 0 months, 1 days
Research summary
Total knee replacement (TKR) is an established treatment for knee osteoarthritis and leads to a satisfactory outcome in over 75% of patients. The pain and function after TKR can be dependent on the accuracy of initial implantation, as deviation of more than 3 degrees from the normal alignment of the limb can lead to abnormal stresses on the implant and accelerated failure. Patient specific cutting blocks may result in a more individualised implant placement, improved pain and function following surgery, and a longer-lasting implant.
This trial is designed to investigate if there is any benefit to bespoke instrumentation in terms of pain and function to the patient, and an economic benefit to the NHS.REC name
South East Scotland REC 01
REC reference
15/SS/0024
Date of REC Opinion
16 Feb 2015
REC opinion
Unfavourable Opinion