BE READY feasibility study

  • Research type

    Research Study

  • Full title

    BEhavioural and Cognitive strategies to get READY for knee replacement (BE READY) Feasibility Study

  • IRAS ID

    257253

  • Contact name

    Chandran Jepegnanam

  • Contact email

    chandran.jepegnanam@manchester.ac.uk

  • Sponsor organisation

    Manchester University NHS Foundation Trust

  • Duration of Study in the UK

    0 years, 11 months, 31 days

  • Research summary

    Total Knee Replacement surgery is offered when older people’s knee joints become worn out and cause pain and problems with daily life. This is successful for most people, but up to 30% of people experience difficulties after surgery and struggle with pain, walking and other activities long-term. Having anxiety or depression before surgery can make problems after surgery more likely. While it is normal to feel apprehensive before surgery, excessive worrying, feeling helpless or having depression can worsen people’s pain experience and prevent them from doing helpful rehabilitation activities. Stress can also disrupt the body’s biological healing processes.

    We aim to test whether 3 sessions of psychological input based on Cognitive Behavioural Therapy (CBT) in small groups can help people with anxiety or depression prepare for surgery. These sessions will help people practice skills like relaxation, plan mood-boosting activities and discuss helpful ways of thinking about pain, surgery and recovery. In Manchester, people awaiting knee surgery are currently offered a short education session to prepare them on for surgery practicalities. This does not directly address low mood and worries about pain and surgery experienced by about 40% of patients. Previous early research reported that 3-4 one-to-one CBT sessions may help; members of the public we asked felt a group would better enable people to share learning and feel supported. This new approach needs to be first tested in a small ‘feasibility’ study to see whether it is acceptable to patients before planning a larger study. The fifteen patients who agree to take part will have the three group sessions in addition to all of their usual care. Data will be collected from participants on mood, knee movement and pain at three time points including 6 months after surgery, helping us understand if and how a larger feasibility trial should go ahead.

  • REC name

    London - Camberwell St Giles Research Ethics Committee

  • REC reference

    20/LO/0637

  • Date of REC Opinion

    20 May 2020

  • REC opinion

    Further Information Favourable Opinion