BC106 Ponto 4 PMCF1

  • Research type

    Research Study

  • Full title

    To investigate the improvement in hearing with the bone anchored hearing solution Ponto 4 on the implanted ear(s).

  • IRAS ID

    279825

  • Contact name

    John FitzGerald

  • Contact email

    john.fitzgerald@nnuh.nhs.uk

  • Sponsor organisation

    Oticon Medical AB

  • Clinicaltrials.gov Identifier

    NCT04761926

  • Duration of Study in the UK

    0 years, 5 months, 1 days

  • Research summary

    BC106 study: Ponto 4 PMS1 Study
    Summary
    This multi-center, single-blinded, prospective study will be conducted at the Norfolk and Norwich University Hospital and University Hospital Bristol. The study is designed to collect data from 34 adult patients with a conductive, mixed hearing loss or single-sided deafness, that are already using a bone-anchored hearing solution (BAHS).
    The purpose of this study is to study the outcome in hearing in terms of ability to hear sounds and understand speech when using Ponto 4, a CE marked bone anchored hearing solution, launched by Oticon Medical AB in June 2019. This will be evaluated through speech tests in quiet and in noise as well as assess the hearing with Ponto 4(s) on and off. Additionally, a patient reported outcome questionnaire evaluating the performance with the Ponto 4(s) after usage in various daily listening situations will be collected from each subject.
    The study consists of 2 visits, Visit 1 and Visit 2 each of approximately 2-2 ½ hours in duration. In between the 2 visits there will be a field trial period of 4-6 weeks where the subject will be asked to use the Ponto 4(s), instead of their own BAHS, in their everyday listening situations.
    At Visit 1, an audiometry (hearing test) will be measured to evaluate whether the subject is eligible for the study. If the subject is found eligible, the Ponto 4 is fitted to the subjects hearing loss following the recommended fitting protocol. A speech in noise test will then be performed with the Ponto 4(s) programmed in two different settings. Subjects will conduct a 4-6 weeks trial period of the Ponto 4(s): between Visit 1 and Visit 2, and they will be asked to fill out a questionnaire regarding their everyday experience with the Ponto 4(s) by the end of this period.
    At Visit 2, the research team will collect the questionnaire and ask subjects to estimate their everyday usage hours of the Ponto 4(s). Speech test in quiet will be conducted with and without the Ponto 4(s). Sound field audiometry will also be performed (hearing test with loudspeakers), with and without the Ponto 4(s). In the end of visit 2, the test leader will ask which BAHS the subject prefers; their own BAHS or the BAHS they used in the study (Ponto 4(s)). The subject will also be asked if they would like to keep the Ponto 4(s).
    34 eligible subjects will be included in the study. If drop-out rate is threatening to jeopardize the power of the study, replacement will be considered and an amendment to the CIP will be prepared accordingly.

  • REC name

    East of England - Cambridge East Research Ethics Committee

  • REC reference

    20/EE/0071

  • Date of REC Opinion

    21 Apr 2020

  • REC opinion

    Further Information Favourable Opinion