Barts Cancer Institute Breast Metastatic Tissue Bank

• Research type

  Research Tissue Bank

• IRAS ID

  173099

• Research summary

  Barts Cancer Institute Breast Metastatic Breast Tissue Bank

• REC name

  East of England - Cambridge Central Research Ethics Committee

• REC reference

  16/EE/0003

• Date of REC Opinion

  30 Mar 2016

• REC opinion

  Further Information Favourable Opinion

• Data collection arrangements

  Samples/data to be stored and collection/consent arrangements (maximum 200 words): This Bank will consent patients for use of samples of metastatic breast cancer for research. Samples are stored in secure, purpose made facilities at Charterhouse Square and Barts Hospital, accessible only to Tissue Bank staff. Access is via swipe card. All samples are kept in locked storage, either freezers, Liquid Nitrogen Tanks or storage cabinets. All related paperwork, including consent forms, are stored in locked filing cabinets in the same area. Patients are consented for storage and use of tissue/blood samples for research along with associated clinicopathological, imaging and treatment data.
  Data is retrieved from the electronic patient record and stored in a purpose made database which is password protected and accessible only by authorised tissue bank staff.

• Research programme

  The Breast Metastatic Tissue Bank is designed to support a broad range of research into metastatic breast disease. Research may involve analysis of DNA, RNA proteins, cells or tissues to assess factors involved in the spread of breast cancer and factors influencing response to treatment. Each project is reviewed by the Tissue Access Committee for suitability and ethical compliance. Data from research projects is returned to the Bank to avoid future duplication and enhance the value of the samples. Researchers from the medical, biomedical, cell biology and bioengineering fields may be involved in use of samples from the Bank, with the aim of better understanding the factors that impact on the transition from primary to metastatic breast cancer, and metastatic tumour growth. A portion of all samples stored are allocated to The Breast Cancer Now Tissue, of which we are a member. This bank is run under the same guidelines as the Barts Cancer Institute Bank.

• Storage license

  12199

• RTBTitle

  Barts Cancer Institute Breast Metastatic Breast Tissue Bank

• Establishment organisation

  Barts Cancer Institute, Centre for Tumour Biology

• Establishment organisation address

  Charterhouse Square

  Barts and The London School of Medicine and Dentistry

  London

  EC1M 6BQ