B7 family proteins in diabetic nephropathy - version 1
Research type
Research Study
Full title
The role of the B7 familly of proteins in diabetic nephropathy
IRAS ID
183558
Contact name
Stephen Kelleher
Contact email
Duration of Study in the UK
3 years, 0 months, 0 days
Research summary
Diabetes is the commonest cause of kidney disease leading to the need for dialysis or transplantation. Proteins that regulate the activation of immune cells and can lead to tissue injury, known as the B7 family of proteins, have recently been implicated in the development of diabetic kidney disease, known as diabetic nephropathy. This study aims to determine whether B7 family members and related signalling molecules are upregulated in kidney biopsy tissue for patients with diabetic nephropathy and other forms of kidney disease.
REC name
London - City & East Research Ethics Committee
REC reference
15/LO/1169
Date of REC Opinion
23 Jun 2015
REC opinion
Favourable Opinion