AZ NSCLC

  • Research type

    Research Study

  • Full title

    Real-World Study of Early-Stage (I, II, III) Non–Small Cell Lung Cancer (NSCLC): Prevalence of EGFR Mutations, Treatment and Outcomes

  • IRAS ID

    299949

  • Contact name

    Jason Chow

  • Contact email

    Jason.chow@stgeorges.nhs.uk

  • Duration of Study in the UK

    0 years, 4 months, 31 days

  • Research summary

    This is a retrospective, noninterventional history study of patients with early stage (I, II, III) non small cell lung cancer. Data collection will be carried out via chart review at participating site in the US, the UK, Canada, Taiwan, South Korea, France, Austria and Germany. Target sample size is 1200 (n=200 in the UK).

    Patient charts to be included will be selected according to the protocol-defined eligibility criteria. Data on each patient will be collected starting at initial diagnosis of NSCLC until the end of available follow-up (i.e., date of mortality, date of last visit, treatment administration or hospitalization, or loss to follow-up). All patients included must have been diagnosed between January 4, 2014 and December 31, 2017. The maximum date of follow-up (retrospectively observed) will be December 31, 2020, allowing up to 7 years of follow-up after the initial NSCLC diagnosis.

  • REC name

    South Central - Hampshire A Research Ethics Committee

  • REC reference

    21/SC/0264

  • Date of REC Opinion

    2 Aug 2021

  • REC opinion

    Favourable Opinion