Autonomic stimulation

  • Research type

    Research Study

  • Full title

    Investigation of the effects of stimulation in patients undergoing stimulation of the nervous system for therapeutic indications.

  • IRAS ID

    215876

  • Contact name

    Alexander L Green

  • Contact email

    alex.green@nds.ox.ac.uk

  • Sponsor organisation

    University of Oxford

  • Duration of Study in the UK

    3 years, 0 months, 1 days

  • Research summary

    Patients routinely undergo invasive stimulation of the nervous system as part of treatment for a variety of conditions including chronic pain, Parkinson’s disease, and ‘movement disorders’. Recently evidence has come to light that stimulation in this manner may have effects on the autonomic nervous system. This may imply that stimulation affects the autonomic nervous system (parameters such as blood pressure, heart rate and sweating) as well as their originally intended indications. We wish to investigate this possibility by testing parameters in patients undergoing these procedures for therapeutic reasons. Our hope is that this will lead to further understanding of the control of the autonomic nervous system, and whether it can be modulated by invasive stimulation.

  • REC name

    London - Queen Square Research Ethics Committee

  • REC reference

    17/LO/0755

  • Date of REC Opinion

    8 Jun 2017

  • REC opinion

    Further Information Favourable Opinion