Automated neutrophil granulation and reactivity as biomarkers

• Research type

  Research Study

• Full title

  Using neutrophil granularity and reactiveness FBC parameters as a biomarker for inflammation or sepsis

• IRAS ID

  340360

• Contact name

  Katie Jones

• Contact email

  Katie.jones2@liverpoolft.nhs.uk

• Sponsor organisation

  Liverpool University Hospitals NHS FT

• Duration of Study in the UK

  1 years, 0 months, 1 days

• Research summary

  Aim: To assess the use of Neutrophil Granularity and Neutrophil Reactiveness Full Blood Count parameters as biomarkers for inflammation or sepsis. This would help identify these conditions early and provide more efficient care for these patients.
  The study will involve comparing in-patients with normal and raised Neutrophil Granularity and Neutrophil Reactiveness, and observing whether there is any correlation between a raised result and the presentation of inflammation in in-patients.

• REC name

  North East - Newcastle & North Tyneside 1 Research Ethics Committee

• REC reference

  25/NE/0067

• Date of REC Opinion

  14 Apr 2025

• REC opinion

  Favourable Opinion