ATTEND
Research type
Research Study
Full title
ATTEND: Attentional Therapy for the TrEatment of Neglect Disorder (ATTEND).
IRAS ID
276250
Contact name
Alexander P Leff
Contact email
Sponsor organisation
University College London
ISRCTN Number
ISRCTN41325767
Clinicaltrials.gov Identifier
UCL Data Protection Registration number, Z6364106/2020/01/96
Duration of Study in the UK
2 years, 11 months, 29 days
Research summary
This study will investigate the treatment of a specific syndrome that can occur following a cerebrovascular accident (Stroke) or brain tumour. Neglect is a complex syndrome characterized by a failure to attend to, look at and respond to stimuli (objects, food, people) located on the side of space or of the body opposite to the side affected by a brain lesion. There is a estimated 3-5 million new cases of neglect world-wide per year (Corbetta, Kincade, Lewis, Snyder, & Sapir, 2005) but no standard treatment for patients with neglect has been established.
The primary objective is to ascertain if immersive virtual reality stimulation that induces smooth pursuit eye movements improves score on impairment-based and function-based outcome measures of neglect in patients with this syndrome, caused by an acute stroke. There will be a control stimulation, delivered by the same VR hardware, which does not induce smooth pursuit eye movements ‘control’.
Secondary outcomes will include reduction in length of stay in an inpatient setting, improvements in social activity and participation, and participant and/or carer reported outcome measures (PROMS/CROMS).
REC name
London - Bromley Research Ethics Committee
REC reference
20/LO/1061
Date of REC Opinion
24 Nov 2020
REC opinion
Further Information Favourable Opinion