Asthma: Phenotyping Exacerbations 3
Research type
Research Study
Full title
Asthma: Phenotyping Exacerbations 3
IRAS ID
304615
Contact name
Matthew Martin
Contact email
Duration of Study in the UK
1 years, 6 months, 31 days
Research summary
Exacerbations of asthma (asthma attacks) are very common in the UK. They are frightening for patients, expensive for the health service, and occasionally lead to avoidable deaths.
Despite the obvious importance of asthma attacks, they remain poorly understood. Although some of the triggers for attacks are known, the resultant characteristics of attacks are not. Recent research has shown different inflammation profiles associated with asthma attacks; however, this is not well understood, and all asthma attacks are treated the same. Increased knowledge about the nature of asthma attacks may better define these attacks and help develop more targeted treatment options.
This study aims to describe the characteristics of patients admitted with asthma attacks. The recovery and response to standard treatment for asthma attacks following discharge from the hospital will also be described.
We will achieve this by studying the characteristics of asthma attacks in patients hospitalized with acute asthma. They will be asked to attend two follow-up visits during which their response to treatment will be described.
The study is planned to last for 2.5 years, with a recruitment period of 18 months, and will include 100 participants with acute asthma.
REC name
HSC REC B
REC reference
22/NI/0003
Date of REC Opinion
21 Jan 2022
REC opinion
Favourable Opinion