Assessment of QoL in patients with long term PoSH
Research type
Research Study
Full title
Assessment of quality of life in patients with long term Post-Surgical Hypoparathyroidism (PoSH)
IRAS ID
245001
Contact name
Sarah Hillary
Contact email
Sponsor organisation
Sheffield Teaching Hospitals NHS Foundation Trust
Duration of Study in the UK
0 years, 4 months, 1 days
Research summary
Post-surgical hypoparathyroidism is an important side effect of thyroid and parathyroid surgery. Given the increasing incidence of thyroid cancer and the rising rates of thyroid surgery, this condition is expected to occur more frequently. Long term PoSH is defined as the need for calcium and/or vitamin D supplements to prevent or treat hypoparathyroidism and/or hypocalcaemia lasting for beyond 6 months after surgery. Although detrimental effects on renal function and other organs have been demonstrated, the impact on patients’ quality of life is poorly documented. It has been suggested that despite medical treatment, all domains of quality of life are affected in patients with PoSH. This study aims to do a detailed assessment of symptoms and quality of life in different cohorts of patients with post-surgical hypoparathyroidism and compare these patients with similar cohorts of patients without hypoparathyroidism. Participants will complete an online questionnaire. Participant will be identified through Multiple Endocrine Neoplasia (MEN) and Oncology Clinics and invited to take part via an on- line questionnaire. Participants may also be signposted to the research via charity (AMEND and Buttefly Thyroid Cancer Trust [BTCT]) websites, whereby they can click on a link to take part in the on-line questionnaire.
REC name
East of Scotland Research Ethics Service REC 2
REC reference
18/ES/0091
Date of REC Opinion
20 Aug 2018
REC opinion
Further Information Favourable Opinion