Assessment of possible benefits of PSG to setup NIV
Research type
Research Study
Full title
The clinical effectiveness of full montage polysomnography vs. limited respiratory polygraphy during non-invasive ventilation set up in chronic obstructive pulmonary (COPD)-obstructive sleep apnoea (OSA) overlap syndrome
IRAS ID
161219
Contact name
Patrick Murphy
Contact email
Sponsor organisation
Guy's & St. Thomas' Foundation NHS Trust
Duration of Study in the UK
0 years, 11 months, 29 days
Research summary
Smoking related lung disease, often called Chronic Obstructive Lung Disease or COPD, remains a common cause of both day and night time symptoms. With increasing rates of obesity in the general population the number of patients who have both COPD and obstructive sleep apnoea, or OSA, which is when patients breathing can stop during the night preventing good quality sleep, is increasing. Whilst the use of breathing machines, or ventilators, to support patients breathing are shown to improve how patients feel and make them less likely to have a ‘flare up’ or exacerbation of their breathing it is not clear what information is required in order to best set the machines up. Different hospitals in different countries use different approaches with some using more monitoring than others.
Study aim
The project intends to evaluate 2 different ways of setting up the ventilators that are used to support patients breathing when sleeping. One method will use more equipment than provides the doctor with more information but may in itself add to discomfort during sleep when setting up the ventilator. The other approach will use less equipment and may therefore interfere less with sleep but will provide less detailed information. We will assess whether both methods produce similar control of peoples breathing in the 3 months following setting up the ventilator.REC name
London - Westminster Research Ethics Committee
REC reference
14/LO/2088
Date of REC Opinion
16 Dec 2014
REC opinion
Further Information Favourable Opinion