Assessment of attendance and impact of “Healthy on Hormones seminars”
Research type
Research Study
Full title
Assessment of attendance and impact of “Healthy on Hormones seminars” for men with metastatic prostate cancer on androgen deprivation therapy
IRAS ID
266229
Contact name
Mieke Van Hemelrijck
Contact email
Sponsor organisation
Guy's & St Thomas' Foundation NHS Trust
Duration of Study in the UK
1 years, 2 months, 2 days
Research summary
Prostate cancer (PCa) is one of the most common cancer types worldwide and a leading cause of morbidity and cancer-related death. In the UK alone, around 50,000 new PCa cases are diagnosed every year. Men with advanced (metastatic) cancer, constitute around 25 % of newly diagnosed cases per year in the UK. Men with metastatic PCa are commonly treated with androgen deprivation therapy (ADT), a cornerstone for management of advanced disease. The use of these treatments reduces testosterone levels (and hence slow down PCa progression), but can result in side-effects such as fatigue and hot flushes, cardiovascular risk factors such as insulin resistance and obesity, erectile dysfunction, osteoporosis as well as mood swings and depression, and thus significantly lowering quality of life. Previous research has demonstrated that lifestyle changes, including diet and exercise, may have a positive impact on survival and quality of life for these men. Hence, our clinical team has developed “Healthy on Hormones”, a series of seminars for men with PCa on ADT (and their partners) at Guy’s Hospital, London. The seminars provide information and strategies to understand ADT and to manage side-effects; including lifestyle advice regarding cardiovascular and skeletal issues associated with ADT treatment. All men who attend the Healthy on Hormones seminars will be invited to follow-up interviews six to ten weeks after the seminars. The interviews will be semi-structured using a topic guide and will investigate the men’s quality of life and correlate this with any lifestyle changes after PCa diagnoses and ADT, as well as after attending the seminars. The aim of this study is to identify additional strategies to promote self-management and lifestyle changes amongst men with PCa on ADT through interviews with men who participated in the seminars which aims to improve quality of life amongst these men.
REC name
East Midlands - Derby Research Ethics Committee
REC reference
19/EM/0340
Date of REC Opinion
15 Nov 2019
REC opinion
Favourable Opinion