Assessment of accommodation in anisometropia with dynamic retinoscopy
Research type
Research Study
Full title
Can anti-accommodation be detected in children with anisometopic amblyopia using Nott dynamic retinoscopy and is it associated with poor visual outcomes?
IRAS ID
229016
Contact name
Sonia Toor
Contact email
Sponsor organisation
Sheffield Children's Hospital
Clinicaltrials.gov Identifier
URMS 154865, University costing project code
Duration of Study in the UK
0 years, 8 months, 28 days
Research summary
Children who have glasses with one lens stronger than the other sometimes have poor vision in the eye with the stronger lens whilst the other eye sees normally. To try and improve vision in the weaker eye, glasses, eye patches and eye drops can be used. In most cases the weaker eye improves but in 15-20% of children there remains a difference in vision between the eyes. This study will compare the focusing ability of children who have equal vision after treatment with children who have one weaker eye despite treatment because research suggests that abnormal focusing may be a reason for persistent reduced vision.
Children aged 5-10 years will be invited, by post, to take part in this study one week before their appointment at the eye department at Sheffield Children’s Hospital. After taking consent children will be asked to watch videos on a laptop placed 1m away from them and on a mobile phone held at 33cm and 50cm. Whilst they are doing this the researcher will shine a light into their eyes to see how much they are focusing. This test is not painful or invasive and will take 20 minutes. Measurements will be taken from both eyes, with and without glasses.
Previous research used found that children whose vision didn’t fully improve after treatment had eyes that focussed independently of each other. However, this equipment is not available in hospitals so this study will use equipment already available in hospitals to see if the same effect can be found. If the same results are found it could help us to predict which children will have a better response to treatment. This means children who are likely to have a poorer outcome from their treatment are given eye patches or drops for a shorter amount of time.
REC name
West Midlands - Coventry & Warwickshire Research Ethics Committee
REC reference
17/WM/0435
Date of REC Opinion
8 Dec 2017
REC opinion
Further Information Favourable Opinion