Assessing novel biomarkers in PICM
Research type
Research Study
Full title
Identifying Novel Biomarkers for the Detection of Pacemaker-Induced Cardiomyopathy (PICM)
IRAS ID
340705
Contact name
Sophie Robinson
Contact email
Sponsor organisation
Sandwell and West Birmingham NHS Trust
Duration of Study in the UK
0 years, 5 months, 1 days
Research summary
This research aims to identify new biomarkers associated with Pacing-Induced Cardiomyopathy (PICM), a condition that can arise in patients requiring long-term heart pacing. By examining these biomarkers alongside echocardiography results and patient histories, the study seeks to improve early detection and management of PICM.
The study will involve a cross-sectional design, collecting data from patients who have undergone pacemaker implantation. Key measurements will include serum levels of specific biomarkers and echocardiographic assessments to evaluate heart function.
The findings could lead to earlier interventions, potentially preventing the progression of PICM to more severe heart failure. This proactive approach may enhance patient outcomes, reduce healthcare costs, and streamline diagnostic processes within the NHS, ultimately benefiting both patients and healthcare providers.
REC name
West Midlands - South Birmingham Research Ethics Committee
REC reference
25/WM/0129
Date of REC Opinion
15 Jul 2025
REC opinion
Further Information Favourable Opinion