ASAS-perSpA

• Research type

  Research Study

• Full title

  ASAS-perSpA Study: Evaluation of peripheral involvement in spondyloarthritis

• IRAS ID

  270446

• Contact name

  Pedro Machado

• Contact email

  pedro.machado@nhs.net

• Sponsor organisation

  Association de Recherche Clinique en Rhumatologie

• Duration of Study in the UK

  0 years, 8 months, 30 days

• Research summary

  ASAS-perSpA Study: Evaluation of peripheral involvement in Spondyloarthritis
  Spondyloarthritis affects your spine and other joints and can be associated with conditions like psoriasis, arthritis related to inflammatory bowel disease, arthritis related to infection and those with childhood onset arthritis. SpA can have several manifestations: buttock and spinal inflammation (known as ‘axial involvement’), inflammation of the joints of the arms and legs (known as ‘peripheral articular involvement’), inflammation at the sites of tendon insertions (known as ‘peripheral entheseal involvement’) and in other organs (known as ‘extra-articular involvement’) such as the skin (e.g. psoriasis), the eye (e.g. uveitis) or the gut (e.g. inflammatory bowel disease).
  The frequency of peripheral involvement in SpA is not yet well known, and it is suspected that patients with skin involvement (i.e. psoriasis) might present more often with peripheral involvement (inflammation of the joints of the arms and legs). Furthermore, it is suspected that the clinical presentation may differ in different countries e.g. patients from South America may have more joints of the arms and legs involved compared to patients from European countries, but no study has investigated such differences.
  A group of rheumatologists at several hospitals worldwide are working together to determine how often peripheral involvement and other clinical features occur in SpA. Once we have information about the different clinical presentations, this will be compared between geographic areas.
  Participants will be included if they have a diagnosis with one of the above conditions that is a part of SpA and they are over 18 years of age.
  The study comprises of one research visit at the patients’ usual clinic, the patient will be asked to fill in questionnaires regarding their condition. They will be examined by a research doctor or nurse

• REC name

  London - Harrow Research Ethics Committee

• REC reference

  19/LO/1733

• Date of REC Opinion

  11 Dec 2019

• REC opinion

  Further Information Favourable Opinion