ARTISAN-SNM 105-0050

  • Research type

    Research Study

  • Full title

    Axonics SacRal NeuromodulaTIon System for UrinAry Urgency Incontinence TreatmeNt: ARTISAN-SNM

  • IRAS ID

    235607

  • Contact name

    M Pakzad

  • Contact email

    Mahreen.pakzad@nhs.net

  • Sponsor organisation

    AXONICS MODULATION TECHNOLOGIES, U.K. LIMITED

  • Clinicaltrials.gov Identifier

    NCT03327948

  • Duration of Study in the UK

    2 years, 2 months, 16 days

  • Research summary

    To evaluate the safety and effectiveness of the Axonics Sacral Neuromodulation System as an aid in the treatment of the symptoms of Urinary Urge Incontinence (UUI) designed to gain pre-market approval in the United States.

    UUI is a problem that causes involuntary leakage of urine with a sudden, strong desire to urinate. Sacral neuromodulation (SNM) is a well-established clinically proven therapy that uses electrical pulses to change bladder nerve activity to treat patients with UUI. Axonics® has developed a new system that includes a rechargeable implantable device and easy to use components to improve patient experiences.
    This study is being conducted to learn more about how well the Axonics SNM System performs in people who have UUI. Up to 145 patients will participate in this study at approximately 20 hospitals located in Europe and North America. All patients enrolled in the study will receive the same treatment.
    Participants will be in the study for about two years and will require at least 10 visits to the study center.

  • REC name

    London - South East Research Ethics Committee

  • REC reference

    18/LO/0047

  • Date of REC Opinion

    31 Jan 2018

  • REC opinion

    Further Information Favourable Opinion