Arterial stiffness and AKI post-CABG

  • Research type

    Research Study

  • Full title

    Is measurement of arterial stiffness a predictor of development of Acute Kidney Injury following elective Coronary Artery Bypass Graft Surgery

  • IRAS ID

    173571

  • Contact name

    Sharlene Greenwood

  • Contact email

    sharlene.greenwood@nhs.net

  • Sponsor organisation

    King's College Hospital

  • Clinicaltrials.gov Identifier

    NCT02364427

  • Duration of Study in the UK

    1 years, 0 months, 6 days

  • Research summary

    Acute Kidney Injury is a condition where your kidneys suddenly stop working properly and usually occurs if you are already unwell with an illness and can happen after having surgery. Having an episode of acute kidney injury increases the risk of progression to chronic kidney disease (CKD) later on and decreases long-term survival. It also has a major socio-economic impact with regards to admissions and length of hospital stay. There is currently no universally accepted treatment or method of identifying patients that are at risk. We aim to measure arterial stiffness in patients prior to them undergoing cardiac surgery to investigate whether this measurement is associated with an increased risk of patients developing acute kidney injury after surgery. We are planning to measure arterial stiffness, and examine a blood sample, for kidney health-related levels to determine whether there is an association between those patients who have stiff arterial vessels and those patients who may develop acute kidney injury after surgery.

  • REC name

    Wales REC 6

  • REC reference

    15/WA/0088

  • Date of REC Opinion

    18 Mar 2015

  • REC opinion

    Further Information Favourable Opinion