Archival genito-urinary tissue, blood, urine, saliva and ascitic fluid

• Research type

  Research Tissue Bank

• IRAS ID

  293610

• Research summary

  Archival genito-urinary tissue, blood, urine, saliva and ascitic fluid collection

• REC name

  East of England - Cambridge Central Research Ethics Committee

• REC reference

  21/EE/0090

• Date of REC Opinion

  22 Apr 2021

• REC opinion

  Favourable Opinion

• Data collection arrangements

  Paraffin embedded samples, frozen tissue and donated blood, urine, saliva and ascitic fluid surplus to diagnostic requirements, are collected from gynaecology and urology patients subject to fully informed consent and held as part of a research tissue bank (RTB) at the Royal Preston Hospital. The consent will also allow access to demographic information and clinical history, all records being held on a dedicated database secured within the hospital network. Samples are anonymised by number and research projects are peer-reviewed by senior clinicians and scientists from the Lancashire Teaching Hospitals and Lancashire Universities Biophotonics and Epigenetic Research Consortium before release to researchers. Tissue is also available to researchers outside the Lancashire Teaching Hospitals and Lancashire Universities Biophotonics and Epigenetic Research Consortium but external REC approval will be requested before tissue release.

• Research programme

  Lancashire Teaching Hospitals and Lancashire Universities Biophotonics and Epigenetic Research Consortium have UK, European and UAE based collaborative research programmes, with clinicians and scientists conducting investigations into novel areas of basic science, diagnosis and treatment of gynaecological and urological tumours. This collaboration comprises researchers from Lancashire Teaching Hospitals Trust; Lancaster University; University of Central Lancashire (UCLan); Section of Molecular Carcinogenesis: Institute of Cancer Research at Sutton; Department of Medical Oncology: Barts and London School of Medicine and Dentistry; Institute of Human nutrition: Berlin University; and the Department of Biochemistry: United Arab Emirates. Previous research projects have had ethical approval to send anonymised tissue to our collaborators in Berlin and UAE.

• Storage license

  12056

• RTBTitle

  Archival genito-urinary tissue, blood, urine, saliva and ascitic fluid collection

• Establishment organisation

  Lancashire Teaching Hospitals NHS Foundation Trust

• Establishment organisation address

  Pathology Department, Royal Preston Hospital

  Sharoe Green Lane, Fulwood

  Preston

  PR2 9HT