Aqueous release to treat IOP spikes post-cataract surgery
Research type
Research Study
Full title
Efficacy and safety of aqueous humour release (burping) performed at the slit-lamp to treat acute intraocular pressure (IOP) spikes post-cataract surgery
IRAS ID
240539
Contact name
Anant Sharma
Contact email
Sponsor organisation
Bedford Hospital
Clinicaltrials.gov Identifier
Duration of Study in the UK
0 years, 6 months, 1 days
Research summary
Intraocular pressure (IOP) rise after cataract surgery is an important and common problem. (Kim et al, 2011) Over 300,000 cataract operations are done per year in the United Kingdom alone (Day et al., 2015). IOP rise can adversely affect vision and can be particularly detrimental in glaucoma patients with preexisting visual field defects (Tranos et al., 2014). The aim of this study is to evaluate the efficacy and safety of aqueous humor release (also known as 'burping' of the wound), a procedure that has been used for decades to quickly reduce acute IOP spikes following cataract surgery. At present there is no published evidence on a standard technique to perform wound 'burping'. Similarly there is uncertainty with regards to the amount and duration of the IOP decrease, and the type and frequency of complications eventually associated. This will be the first research project formally evaluating this procedure. This study will also help allay issues over fluid release in high IOPs and consequences of such dramatic IOP drop which concerns ophthalmologists who do not routinely use this technique.
REC name
East of England - Cambridgeshire and Hertfordshire Research Ethics Committee
REC reference
18/EE/0185
Date of REC Opinion
9 Oct 2018
REC opinion
Further Information Favourable Opinion