APD334003_ OASIS_Version 1

  • Research type

    Research Study

  • Full title

    A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Multi-Center Study to Investigate the Safety and Efficacy of APD334 in Patients with Moderately to Severely Active Ulcerative Colitis

  • IRAS ID

    184353

  • Contact name

    James Lindsay

  • Contact email

    james.lindsay@bartsandthelondon.nhs.uk

  • Sponsor organisation

    Arena Pharmaceuticals, Inc.

  • Eudract number

    2015-001942-28

  • Duration of Study in the UK

    0 years, 10 months, 14 days

  • Research summary

    The purpose of this study is to find out about the safety and efficacy of APD334 for the treatment of moderately to severely active ulcerative colitis. APD334 is an experimental drug which has not yet been approved by Health Authorities including the MHRA (Medicines and Healthcare Products Regulatory Agency) for the treatment of moderately or severely active ulcerative colitis.
    APD334 is being investigated to treat so-called autoimmune diseases, specifically inflammatory bowel diseases such as ulcerative colitis. APD334 is an oral drug (tablet or capsule) aimed to reduce the inflammation in the gut in patients with moderately to severely active ulcerative colitis.

  • REC name

    London - South East Research Ethics Committee

  • REC reference

    15/LO/1876

  • Date of REC Opinion

    12 Jan 2016

  • REC opinion

    Further Information Favourable Opinion